Raheem Sterling also scored his fourth and fifth goals of the season to leave Roy Hodgson still seeking his first points as Eagles manager.
Leroy Sane broke the deadlock with a sublime solo finish on 44 minutes. The German controlled a David Silva pass and flicked over the head of Scott Dann before beating Wayne Hennessey from a tight angle.
Sterling then converted twice within eight minutes from crosses by Sane and Aguero. Aguero headed in Sane’s second assist and substitute Fabian Delph curled in from distance to keep Pep Guardiola’s side unbeaten.
Man City’s superior goal record means they are above Manchester United on 16 points. Palace stay bottom and are only the second team in PL history to lose their first six matches of a season.
Watch Video of Goals and Highlights Here!
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